Verner J, Humpolícek P, Knoll A
Department of Animal Morphology, Physiology and Genetics, Mendel University of Agriculture and Forestry, Brno, Czech Republic.
J Anim Breed Genet. 2007 Apr;124(2):81-5. doi: 10.1111/j.1439-0388.2007.00639.x.
Porcine myogenic differentiation genes (MYOD) family play a key role in growth and muscle development and are therefore considered as candidate genes for meat production traits. The objective of the study was to investigate the polymorphisms at four loci belonging to the MYOD genes family and analyse their associations with variation in meat production traits in Czech pig breeds. To verify the associations between the polymorphisms and the selected meat traits, altogether 254 pigs, including full- and half-sibs, of Large White and Landrace breeds were tested. The studied meat characteristics were weight of neck, loin, shoulder and ham, lean meat content (LMC), backfat thickness, intramuscular fat (IMF), remission, dry matter content and test daily gain. Statistically significant associations were observed between MYOG gene and fat and neck weight, and between MYF5 gene and IMF and LMC. High significant differences were observed between genotypes AA and AB of MYOD1 in IMF and between genotypes AB and BB of MYF5 in loin weight.
猪肌生成分化基因(MYOD)家族在生长和肌肉发育中起关键作用,因此被视为肉类生产性状的候选基因。本研究的目的是调查属于MYOD基因家族的四个位点的多态性,并分析它们与捷克猪品种肉类生产性状变异的关联。为了验证多态性与所选肉质性状之间的关联,共对254头大白猪和长白猪品种的猪(包括全同胞和半同胞)进行了测试。所研究的肉质特征包括颈部、腰部、肩部和火腿的重量、瘦肉含量(LMC)、背膘厚度、肌内脂肪(IMF)、缓解率、干物质含量和日增重。观察到MYOG基因与脂肪和颈部重量之间存在统计学显著关联,MYF5基因与IMF和LMC之间存在统计学显著关联。在IMF方面,MYOD1的AA基因型和AB基因型之间以及在腰部重量方面,MYF5的AB基因型和BB基因型之间观察到高度显著差异。