Knust Elisabeth, Huttner Wieland B
Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany.
Dev Cell. 2007 May;12(5):664-6. doi: 10.1016/j.devcel.2007.04.006.
Apical-basal polarity of epithelial cells is critical for their symmetric versus asymmetric division and commonly thought to be established in interphase. In a novel type of cell division termed "mirror-symmetric", apical cell constituents accumulate during M-phase at the cleavage furrow, resulting in epithelial daughter cells with opposite apical-basal polarity.
上皮细胞的顶-基极性对于其对称与不对称分裂至关重要,通常认为是在间期建立的。在一种称为“镜像对称”的新型细胞分裂中,顶端细胞成分在M期于分裂沟处积累,导致上皮子细胞具有相反的顶-基极性。