神经细胞中二十二碳六烯酸的新代谢途径。 - Suppr

Novel metabolism of docosahexaenoic acid in neural cells.

作者信息

Kim Hee-Yong

机构信息

Laboratory of Molecular Signaling, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892-9410, USA.

出版信息

J Biol Chem. 2007 Jun 29;282(26):18661-5. doi: 10.1074/jbc.R700015200. Epub 2007 May 8.

DOI:10.1074/jbc.R700015200

PMID:17488715

Abstract

摘要

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Novel metabolism of docosahexaenoic acid in neural cells.神经细胞中二十二碳六烯酸的新代谢途径。

J Biol Chem. 2007 Jun 29;282(26):18661-5. doi: 10.1074/jbc.R700015200. Epub 2007 May 8.

A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell signalling throughout evolution.一个关于二十二碳六烯酸在整个进化过程中对神经细胞信号传递不可替代作用的量子理论。

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Cerebral endothelium and astrocytes cooperate in supplying docosahexaenoic acid to neurons.脑内皮细胞和星形胶质细胞协同作用，为神经元提供二十二碳六烯酸。

Adv Exp Med Biol. 1993;331:229-33. doi: 10.1007/978-1-4615-2920-0_36.

Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid.体内由二十二碳六烯酸形成新型D环和E环类异前列腺素化合物（D4/E4-神经前列腺素）。

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Decrease in neuron size in docosahexaenoic acid-deficient brain.二十二碳六烯酸缺乏的大脑中神经元大小减小。

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Astrocytes, not neurons, produce docosahexaenoic acid (22:6 omega-3) and arachidonic acid (20:4 omega-6).星形胶质细胞而非神经元产生二十二碳六烯酸（22:6 ω-3）和花生四烯酸（20:4 ω-6）。

J Neurochem. 1991 Feb;56(2):518-24. doi: 10.1111/j.1471-4159.1991.tb08180.x.

[Inhibitory effects of docosahexaenoic acid (DHA)-derived metabolites on vasoconstrictions].[二十二碳六烯酸（DHA）衍生代谢物对血管收缩的抑制作用]

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N-Docosahexaenoylethanolamine: A neurotrophic and neuroprotective metabolite of docosahexaenoic acid.二十二碳六烯酰乙醇胺：二十二碳六烯酸的神经营养和神经保护代谢物。

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Polyunsaturated fatty acid synthesis and release by brain-derived cells in vitro.脑源细胞在体外合成及释放多不饱和脂肪酸

J Mol Neurosci. 2001 Apr-Jun;16(2-3):195-200; discussion 215-21. doi: 10.1385/JMN:16:2-3:195.

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Novel metabolism of docosahexaenoic acid in neural cells.

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