Carnes D, Parsons S, Ashby D, Breen A, Foster N E, Pincus T, Vogel S, Underwood M
Centre for Health Sciences, Barts and The London, Queen Mary School of Medicine and Dentistry, 2 Newark St, London, E1 2AT, UK.
Rheumatology (Oxford). 2007 Jul;46(7):1168-70. doi: 10.1093/rheumatology/kem118. Epub 2007 May 7.
To investigate the frequency and health impact of chronic multi-site musculoskeletal pain, in a representative UK sample.
Population postal questionnaire survey, using 16 general practices in the southeast of England, nationally representative urban/rural, ethnic and socioeconomic mix. A random selection of 4049 registered patients, aged 18 or over, were sent a questionnaire. The main outcome measures were chronic pain location, identified using a pain drawing; distress, pain intensity and disability as measured by the GHQ12 and the Chronic Pain Grade.
A total of 2445 patients (60%) responded to the survey (44% male, mean age 52 yrs); 45% had chronic musculoskeletal pain. Of those with chronic pain, three quarters had pain in multiple sites (two or more sites). Variables significantly predicting this were: age under 55, [odds ratio (OR) 0.5, 95% confidence interval (CI) 0.4, 0.6]; psychological distress (OR 1.8, CI at 95% 1.4, 2.2) and high pain intensity (OR 5.2, CI at 95% 4.1, 6.7). Only 33% of multi-site pain distributions conformed to the American College of Rheumatology definition of chronic widespread pain.
Multi-site chronic pain is more common than single-site chronic pain and is commonly associated with other problems. Indiscriminate targeting of research and care for chronic musculoskeletal pain on single sites may often be inappropriate.
在具有代表性的英国样本中,调查慢性多部位肌肉骨骼疼痛的发生率及其对健康的影响。
采用邮寄问卷调查法,选取英格兰东南部16家全科诊所,这些诊所具有全国代表性的城乡、种族和社会经济构成。随机抽取4049名18岁及以上的注册患者,向其发送问卷。主要观察指标包括:使用疼痛图确定的慢性疼痛部位;采用GHQ12和慢性疼痛分级量表测量的痛苦程度、疼痛强度和残疾情况。
共有2445名患者(60%)回复了调查(男性占44%,平均年龄52岁);45%的患者患有慢性肌肉骨骼疼痛。在患有慢性疼痛的患者中,四分之三的人有多个部位疼痛(两个或更多部位)。显著预测这一情况的变量包括:55岁以下(比值比[OR]0.5,95%置信区间[CI]0.4,0.6);心理困扰(OR 1.8,95%CI 1.4,2.2)和高疼痛强度(OR 5.2,95%CI 4.1,6.7)。只有33%的多部位疼痛分布符合美国风湿病学会对慢性广泛性疼痛 的定义。
多部位慢性疼痛比单部位慢性疼痛更常见,且通常与其他问题相关。将慢性肌肉骨骼疼痛的研究和治疗不加区分地针对单一部位往往可能不合适。