Geisler J P, Linnemeier G C, Manahan K J
Indiana Women's Oncology, St. Vincent Hospitals, Indianapolis, Indiana, USA.
Int J Gynaecol Obstet. 2007 Jul;98(1):39-43. doi: 10.1016/j.ijgo.2007.03.035. Epub 2007 May 8.
The purpose is to determine the rate of lymph node metastases in women with endometrioid adenocarcinoma of the endometrium (EAE) undergoing systematic lymphadenectomy.
Patients (349) underwent a complete pelvic and para-aortic lymphadenectomy from caudal to the median circumflex to the level of the renal vessels.
Grade 1 tumors accounted for 32.7% of the tumors and 31.0% of the positive nodes, grade 2 accounted for 47.3% of the tumors (37.9% of positive nodes), and grade 3 accounted for 20.1% of the tumors and 31.0% of the positive nodes (P>0.05). Positive nodes were found in 15.8% of grade 1 tumors, 13.3% of grade 2 tumors and 25.7% of grade 3 tumors (P>0.05). Isolated para-aortic involvement without pelvic nodal involvement occurred in 29% of patients with positive nodes.
When complete lymphadenectomies are performed in EAE, positive lymph nodes (including isolated para-aortic lymph nodes) are common in all grades.
目的是确定接受系统性淋巴结清扫术的子宫内膜样腺癌（EAE）女性患者的淋巴结转移率。
349例患者接受了从尾侧至旋髂深动脉中部至肾血管水平的全盆腔及腹主动脉旁淋巴结清扫术。
1级肿瘤占肿瘤总数的32.7%，阳性淋巴结占31.0%；2级肿瘤占肿瘤总数的47.3%（阳性淋巴结占37.9%）；3级肿瘤占肿瘤总数的20.1%，阳性淋巴结占31.0%（P>0.05）。1级肿瘤中15.8%发现阳性淋巴结，2级肿瘤中13.3%发现阳性淋巴结，3级肿瘤中25.7%发现阳性淋巴结（P>0.05）。在有阳性淋巴结的患者中，29%出现孤立的腹主动脉旁转移而无盆腔淋巴结转移。
在EAE患者中进行完全淋巴结清扫术时，所有分级的患者中出现阳性淋巴结（包括孤立的腹主动脉旁淋巴结）都很常见。
