Nilsson Anders S, Haggård-Ljungquist Elisabeth
Department of Genetics, Microbiology, and Toxicology, University of Stockholm, SE-10691 Stockholm, Sweden.
Res Microbiol. 2007 May;158(4):311-7. doi: 10.1016/j.resmic.2007.02.004. Epub 2007 Mar 3.
The structural genes of P2-like phages are almost identical between different isolates of Escherichia coli, whereas the regulatory genes and host integration sites are more variable. The variation in P2-like phages infecting other gamma-proteobacteria is broader, but their structural genes seem to follow the evolution of their host bacteria. Taken together, this suggests that P2-like phages and their hosts are coevolving.
在不同的大肠杆菌分离株中，P2样噬菌体的结构基因几乎相同，而调控基因和宿主整合位点则更具变异性。感染其他γ-变形菌的P2样噬菌体的变异范围更广，但其结构基因似乎遵循其宿主细菌的进化。综上所述，这表明P2样噬菌体与其宿主正在共同进化。
