Kunz U, Friedrich T
Frauenklinik, Spital Zollikerberg, Institut für Pathologie medica, Zürich.
Praxis (Bern 1994). 2007 Apr 25;96(17):681-6. doi: 10.1024/1661-8157.96.17.681.
Less than 1% of primary malignant breast tumours are sarcomas. Malignant fibrous histiocytoma (MFH) are rare among them. Prospective randomized studies are impossible because of the rarity of cases. There is an increase of reported cases of sarcoma of the breast after organ-conserving therapies of breast carcinoma and postoperative irradiation. Even if MFH of the breast is very rare, the incidence rate is likely to increase with the rise of organ-conserving therapy of breast carcinoma. Therefore, efforts to optimize the therapy are justified. MFH should be included in the differential diagnosis in cases of large tumour diameters, rapidly progressive tumour growth and absence of axillary lymph nodes or distant metastasis. The report deals with a 90-year-old patient with exulcerated MFH of the left breast. It is not known whether she had any prior radiotherapy.
原发性恶性乳腺肿瘤中肉瘤占比不到1%。其中恶性纤维组织细胞瘤(MFH)较为罕见。由于病例稀少,前瞻性随机研究无法开展。在乳腺癌保乳治疗和术后放疗后,乳腺肉瘤的报告病例有所增加。即使乳腺MFH非常罕见,但随着乳腺癌保乳治疗的增加,其发病率可能会上升。因此,努力优化治疗是合理的。对于肿瘤直径大、肿瘤生长迅速且无腋窝淋巴结或远处转移的病例,应将MFH纳入鉴别诊断。本文报告了一名90岁左乳溃疡性MFH患者。尚不清楚她之前是否接受过放疗。