Ushijima S, Minagawa M, Kiyohara K, Kim J, Kitagawa S, Nakagawa M, Segawa Y
Nihon Geka Gakkai Zasshi. 1987 Jan;88(1):119-22.
Although malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma of adult, it rarely arises in the breast tissue. Only seven cases have been previously reported in Japan. One case of the MFH of the mammary gland is presented in this paper. A 39 year old woman, who had received no radiation, was referred to our hospital due to a painful right breast lump. Excisional biopsy revealed yellowish white soft tumor with an obscured margin. Histological, tumor was composed of spindle shaped cells of a storiform pattern, which was diagnosed as MFH of the breast. Radical mastectomy (Br + Mj + Ax) was added to this patient. The tumor invaded to the fat tissue without metastasis to the axillary lymph nodes. We performed the post-operative adjuvant chemotherapy of Adriamycin. She made an uneventful recovery and is now free of disease eleven months postoperatively.
尽管恶性纤维组织细胞瘤(MFH)是成人最常见的软组织肉瘤,但它很少发生于乳腺组织。此前日本仅报道过7例。本文报告1例乳腺MFH。一名39岁未接受过放疗的女性因右侧乳腺疼痛性肿块转诊至我院。切除活检显示为边界不清的黄白色软肿瘤。组织学检查显示,肿瘤由呈车辐状排列的梭形细胞组成,诊断为乳腺MFH。该患者接受了根治性乳房切除术(Br + Mj + Ax)。肿瘤侵犯脂肪组织,但未转移至腋窝淋巴结。我们对其进行了阿霉素术后辅助化疗。她恢复顺利,术后11个月无疾病复发。