Nakamura Shigeki, Miyazaki Yoshitsugu, Mihar Tomo, Seki Masafumi, Izumikawa Koichi, Yanagihara Katsunori, Ohno Hideaki, Higashiyama Yasuhito, Hirakata Youichi, Soejima Yoshifumi, Tashiro Takayoshi, Kohno Shigeru
National Hospital Organizaion Ureshino Medical Hospital.
Nihon Kokyuki Gakkai Zasshi. 2007 Apr;45(4):356-60.
A 79-year-old woman was admitted to the Department of Orthopedics Surgery for treatment of osteoarthritis in her knee. Multiple pulmonary nodular lesions were found on preoperative chest x-ray film screening. Metastatic lung tumor was suspected, but no tumorous lesions were detected in other organs. CT guided lung biopsy was performed. Histopathological examination revealed amyloid consisting of homogenous eosinophilic materials. No amyloid deposits were detected in other organs, so we diagnosed localized nodular pulmonary amyloidosis. She was subsequently given a diagnosis of primary Sjögren syndrome. We believe that such a case of multiple nodular pulmonary amyloidosis with Sjögren syndrome is rare, and the case showed interesting radiological findings, such as mimicking metastatic lung tumor.
一名79岁女性因膝关节骨关节炎入住骨科接受治疗。术前胸部X光片筛查发现多个肺结节性病变。怀疑为肺转移瘤,但其他器官未检测到肿瘤性病变。遂进行CT引导下肺活检。组织病理学检查显示淀粉样物质由均匀的嗜酸性物质组成。其他器官未检测到淀粉样沉积物,因此我们诊断为局限性结节性肺淀粉样变。随后她被诊断为原发性干燥综合征。我们认为这种合并干燥综合征的多发性结节性肺淀粉样变病例罕见,且该病例显示出有趣的影像学表现,如类似肺转移瘤。