Saito Sayaka, Murakami Takashi, Suzuki Kichiya, Terada Yukihiro, Fukushima Kouhei, Moriya Takuya
Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Fertil Steril. 2007 Oct;88(4):969.e7-9. doi: 10.1016/j.fertnstert.2006.12.082. Epub 2007 May 10.
To report a rare complication of GnRH agonist therapy for intestinal endometriosis.
Case report.
University hospital.
PATIENT(S): A 45-year-old nulliparous Japanese woman with catamenial digestive symptoms.
INTERVENTION(S): GnRH agonist therapy.
MAIN OUTCOME MEASURE(S): Acute abdomenal crisis with free air in the abdominal X-ray.
RESULT(S): An emergency laparotomy showed both an ileal constriction and perforation. An ileocecal enterectomy with an end-to-end anastomosis was performed. A pathological examination of the ileum revealed ileal endometriosis.
CONCLUSION(S): Flare-up of intestinal endometriosis induced by GnRH agonist has the potential to lead to intestinal perforation. Careful diagnosis and treatment are necessary for cyclic and periodic gastrointestinal manifestation.
报告GnRH激动剂治疗肠道子宫内膜异位症的一种罕见并发症。
病例报告。
大学医院。
一名45岁未生育的日本女性，有经期消化症状。
GnRH激动剂治疗。
腹部X线显示有游离气体的急性腹部危机。
急诊剖腹手术显示回肠狭窄和穿孔。进行了回盲部肠切除术并端端吻合。回肠病理检查显示回肠子宫内膜异位症。
GnRH激动剂诱发的肠道子宫内膜异位症发作有可能导致肠穿孔。对于周期性和间歇性胃肠道表现，需要仔细诊断和治疗。
