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莫洛尼鼠白血病病毒（MuLV）和猴空泡病毒40（SV40）对体外培养的小鼠成纤维细胞衰老的影响。

The influence of MuLV and SV40 viruses on senescence in mouse fibroblasts in vitro.

作者信息

Baker R S

出版信息

Experientia. 1976 Jan 15;32(1):98-9. doi: 10.1007/BF01932644.

DOI:10.1007/BF01932644
PMID:174938
Abstract

Mouse cells productively infected with Moloney leukaemia virus (MuLV) underwent senescence in a manner similar to control cells, although they recovered more readily as an established line. Rapidly growing cell lines were also obtained following simian virus 40 (SV40) infection of senescent cells. However, superinfection of senescent MuLV-producing cells by SV40 led to slower growing cells with a reduced output of infectious MuLV.

摘要

被莫洛尼白血病病毒（MuLV）有效感染的小鼠细胞，其衰老方式与对照细胞相似，尽管作为一个既定细胞系它们更容易恢复。衰老细胞感染猿猴病毒40（SV40）后也获得了快速生长的细胞系。然而，SV40对衰老的MuLV产生细胞进行超感染会导致细胞生长变慢，传染性MuLV的产量降低。

相似文献

1
The influence of MuLV and SV40 viruses on senescence in mouse fibroblasts in vitro.莫洛尼鼠白血病病毒（MuLV）和猴空泡病毒40（SV40）对体外培养的小鼠成纤维细胞衰老的影响。
Experientia. 1976 Jan 15;32(1):98-9. doi: 10.1007/BF01932644.
2
Immunosuppression by spleen cells from Moloney leukemia. III. Evidence for a suppressor cell that is not the leukemic, virus-producing cell.莫洛尼白血病脾细胞引起的免疫抑制。III. 一种并非白血病病毒产生细胞的抑制细胞的证据。
J Immunol. 1977 Sep;119(3):1097-101.
3
Leukaemogenesis by the delta Mo + SV Moloney murine leukaemia virus (M-MuLV) variant in E mu pim-1 transgenic mice: high frequency of recombination with a solo endogenous M-MuLV LTR in vivo.Eμpim-1转基因小鼠中δMo + SV莫洛尼氏鼠白血病病毒（M-MuLV）变体引发白血病：体内与单个内源性M-MuLV长末端重复序列（LTR）的高频重组
J Gen Virol. 1995 Feb;76 ( Pt 2):347-56. doi: 10.1099/0022-1317-76-2-347.
4
Retrovirus-induced changes in major histocompatibility complex antigen expression influence susceptibility to lysis by cytotoxic T lymphocytes.逆转录病毒引起的主要组织相容性复合体抗原表达变化影响细胞毒性T淋巴细胞介导的裂解敏感性。
J Immunol. 1985 Oct;135(4):2287-92.
5
Mechanisms of leukemogenesis. I. Generation of autoreactive lymphocytes in response to a murine leukemia virus.白血病发生的机制。I. 对鼠白血病病毒产生自身反应性淋巴细胞。
J Immunol. 1979 May;122(5):1874-80.
6
Presence of antibody against mouse fetal antigen in the sera from C57BL-6 mice immunized with Rauscher leukemia.用劳氏肉瘤病毒免疫的C57BL - 6小鼠血清中抗小鼠胎儿抗原抗体的存在情况。
Cancer Res. 1972 Nov;32(11):2332-7.
7
The immune response to Moloney murine leukemia virus-induced tumors: induction of cytolytic T lymphocytes specific for both viral and tumor-associated antigens.对莫洛尼鼠白血病病毒诱导肿瘤的免疫反应：诱导针对病毒和肿瘤相关抗原的细胞毒性T淋巴细胞。
J Immunol. 1986 Dec 15;137(12):3968-72.
8
Endogenous retroviral env expression in primary murine leukemias: lack of xenotropic antigens but presence of distinct mink cell focus-forming env subtypes correlating with ecotropic virus inoculated and mouse strain.内源性逆转录病毒env在原发性小鼠白血病中的表达：缺乏嗜异性抗原，但存在与嗜亲性病毒接种及小鼠品系相关的不同的貂细胞灶形成env亚型。
J Natl Cancer Inst. 1987 Jan;78(1):181-9. doi: 10.1093/jnci/78.1.181.
9
In vitro studies of cell-mediated immunity to Moloney murine leukemia virus and Moloney leukemia-associated surface antigens.针对莫洛尼鼠白血病病毒和莫洛尼白血病相关表面抗原的细胞介导免疫的体外研究。
Cancer Res. 1979 Dec;39(12):4887-93.
10
Abelson antigen: a viral tumor antigen that is also a differentiation antigen of BALB/c mice.阿贝尔森抗原：一种病毒肿瘤抗原，也是BALB/c小鼠的分化抗原。
Proc Natl Acad Sci U S A. 1978 Aug;75(8):3918-22. doi: 10.1073/pnas.75.8.3918.

本文引用的文献

1
Requirements for RNA and DNA synthesis in the transformation of mouse embryo cells by murine sarcoma virus (Moloney).莫洛尼鼠肉瘤病毒对小鼠胚胎细胞进行转化时RNA和DNA合成的要求。
J Gen Virol. 1969 Apr;4(3):457-60. doi: 10.1099/0022-1317-4-3-457.
2
Properties of mouse embryo cells infected with murine sarcoma virus and simian virus 40 simultaneously in vitro.体外同时感染鼠肉瘤病毒和猿猴病毒40的小鼠胚胎细胞的特性
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Alterations of mouse embryo cells during in vitro aging.
Exp Cell Res. 1973 Jan;76(1):186-90. doi: 10.1016/0014-4827(73)90434-5.
4
Stimulation of DNA synthesis and enhancement of murine sarcoma virus replication in mouse embryo cells by SV 40.SV40对小鼠胚胎细胞中DNA合成的刺激及对鼠肉瘤病毒复制的增强作用。
J Gen Virol. 1972 Jan;14(1):115-7. doi: 10.1099/0022-1317-14-1-115.
5
Increased transformation efficiency of Simian virus 40 in rat embryo cells infected with Rauscher leukaemia virus.在感染劳斯氏白血病病毒的大鼠胚胎细胞中，猿猴病毒40的转化效率提高。
Nat New Biol. 1971 Mar 17;230(11):81-3. doi: 10.1038/newbio230081a0.
6
Different cell culture characteristics of two strains of murine sarcoma virus.两株鼠肉瘤病毒的不同细胞培养特性
Proc Soc Exp Biol Med. 1969 Jun;131(2):454-6. doi: 10.3181/00379727-131-33900.
7
A viral interference test for mouse leukemia viruses.小鼠白血病病毒的病毒干扰试验。
Virology. 1967 Sep;33(1):180-4. doi: 10.1016/0042-6822(67)90111-0.
8
Transformation assay for murine sarcoma viruses using a Simian virus 40-transformed human cell line.使用猴病毒40转化的人细胞系对鼠肉瘤病毒进行转化试验。
J Natl Cancer Inst. 1974 Jan;52(1):167-71. doi: 10.1093/jnci/52.1.167.
9
Alterations in the susceptibility of cultured mouse cells to transformation by murine sarcoma virus (HARVEY).
J Gen Virol. 1971 Aug;12(2):95-104. doi: 10.1099/0022-1317-12-2-95.