小鼠染色体中核糖体RNA基因数量的变异
Variation in ribosomal RNA gene number in mouse chromosomes.
作者信息
Henderson A S, Eicher E M, Yu M T, Atwood K C
机构信息
Department of Human Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY, USA.
出版信息
Cytogenet Cell Genet. 1976;17(6):307-16. doi: 10.1159/000130733.
PMID:17494622
Abstract
Hybridization of 125-I-ribosomal RNA to mouse chromosomes in situ produced significant differences in grain count at known rDNA sites, depending on the strains from which they were derived. This is interpreted to mean that the number of rRNA genes in a given nucleolar chromosome, and in the entire genome, is polymorphic among strains and among outbred individuals.
摘要
将¹²⁵-I-核糖体RNA与小鼠染色体进行原位杂交，在已知的核糖体DNA位点上，根据其来源菌株的不同，产生了明显的颗粒计数差异。这被解释为意味着在给定的核仁染色体以及整个基因组中，rRNA基因的数量在不同菌株和远交个体中是多态性的。
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