钆喷酸葡胺增强磁共振成像在隐球菌性脑膜脑炎中的应用

Gd-DTPA-enhanced MR imaging of cryptococcal meningoencephalitis.

作者信息

Takasu A, Taneda M, Otuki H, Okamoto Y, Oku K

机构信息

Department of Neurosurgery, Hanwa Memorial Hospital, Osaka, Japan.

出版信息

Neuroradiology. 1991;33(5):443-6. doi: 10.1007/BF00598622.

DOI:10.1007/BF00598622

PMID:1749478

Abstract

This report describes magnetic resonance (MR) imaging of biopsy-proved cryptococcal central nervous system (CNS) infection in a 31-year-old HIV negative man. Initial MR imaging revealed multi-focal Gd-DTPA enhancement and showed more lesions than contrast enhanced CT. The lesions regressed after antifungal therapy. MR imaging aids in diagnosis as well as helps to monitor the response to the pharmacological therapy of cryptococcal meningoencephalitis and possibly provides valuable insights into the pathophysiology of this condition.

摘要

本报告描述了一名31岁HIV阴性男性经活检证实的新型隐球菌中枢神经系统（CNS）感染的磁共振（MR）成像。最初的MR成像显示多灶性钆喷酸葡胺（Gd-DTPA）强化，且显示出比增强CT更多的病变。抗真菌治疗后病变消退。MR成像有助于诊断，也有助于监测新型隐球菌性脑膜脑炎药物治疗的反应，并可能为这种疾病的病理生理学提供有价值的见解。