Tenser R B, Viselli A L, Savage D H
Department of Medicine, Penn State University College of Medicine, Hershey 17033.
Neurosci Lett. 1991 Sep 2;130(1):85-8. doi: 10.1016/0304-3940(91)90233-j.
Herpes simplex virus (HSV) frequently infects human sensory ganglion neurons, and similar infections have been reported in experimental animals. Reported here is an investigation of in vivo neuronal function after HSV infection. It was observed that the proportion of fluoride resistant acid phosphatase (FRAP)-positive trigeminal ganglion neurons was decreased for several months after experimental infection of mice, and it is suggested that other neuronal functions may also be altered by HSV.
单纯疱疹病毒(HSV)经常感染人类感觉神经节神经元,并且在实验动物中也有类似感染的报道。本文报道了一项关于HSV感染后体内神经元功能的研究。观察到在小鼠实验感染后的几个月里,耐氟酸性磷酸酶(FRAP)阳性三叉神经节神经元的比例下降,提示HSV可能还会改变其他神经元功能。