肯尼亚基苏木年轻男性中普遍存在的HIV-1感染的性行为及危险因素的巢式病例对照研究。
A nested case-control study of sexual practices and risk factors for prevalent HIV-1 infection among young men in Kisumu, Kenya.
作者信息
Mattson Christine L, Bailey Robert C, Agot Kawango, Ndinya-Achola J O, Moses Stephen
机构信息
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
出版信息
Sex Transm Dis. 2007 Oct;34(10):731-6. doi: 10.1097/01.olq.0000261335.42480.89.
Abstract
OBJECTIVES
To investigate sexual practices and risk factors for prevalent HIV infection among young men in Kisumu, Kenya.
GOAL
The goal of this study was to identify behaviors associated with HIV in Kisumu to maximize the effectiveness of future prevention programs.
STUDY DESIGN
Lifetime sexual histories were collected from a nested sample of 1337 uncircumcised participants within the context of a randomized controlled trial of male circumcision to reduce HIV incidence.
RESULTS
Sixty-five men (5%) tested positive for HIV. Multiple logistic regression revealed the following independent predictors of HIV: older age, less education, being married, being Catholic, >4 lifetime sex partners, prior treatment for an STI, sex during partner's menstruation, ever practicing bloodletting, and receipt of a medical injection in the last 6 months. Prior HIV testing and postcoital cleansing were protective.
CONCLUSIONS
This analysis confirms the importance of established risk factors for HIV and identifies practices that warrant further investigation.
摘要
目的
调查肯尼亚基苏木年轻男性的性行为及当前艾滋病毒感染的风险因素。
目标
本研究的目标是确定基苏木与艾滋病毒相关的行为，以最大限度地提高未来预防项目的有效性。
研究设计
在一项旨在降低艾滋病毒发病率的男性包皮环切随机对照试验中，从1337名未行包皮环切术的参与者的嵌套样本中收集终生性史。
结果
65名男性（5%）艾滋病毒检测呈阳性。多因素逻辑回归显示艾滋病毒的以下独立预测因素：年龄较大、受教育程度较低、已婚、为天主教徒、终生性伴侣>4个、既往有性传播感染治疗史、在伴侣月经期间发生性行为、曾放血、以及在过去6个月内接受过医疗注射。既往艾滋病毒检测和性交后清洗具有保护作用。
结论
该分析证实了既定艾滋病毒风险因素的重要性，并确定了值得进一步调查的行为。
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