Kerhornou Arnaud, Guigó Roderic
Centre de Regulacio Genomica, Institut Municipal d'Investigació Mèdica and Universitat Pompeu Fabra, Pg. Maritim de la Barceloneta, 08003 Barcelona, Catalonia, Spain.
Bioinformatics. 2007 Jul 15;23(14):1831-3. doi: 10.1093/bioinformatics/btm252. Epub 2007 May 12.
Here we present a computational protocol to analyze the promoter regions of a given set of co-expressed genes, and its implementation through the use of Web services technologies. This protocol aims to cluster a set of co-regulated genes in subsets of genes showing similar configurations of transcription factor binding sites. All the steps of this protocol have been developed as web services that are compliant with BioMoby specifications.
{http://genome.imim.es/cgi-bin/moby/GeneClustering_DataSubmission.cgi}.
Supplementary data are available at {http://genome.imim.es/webservices/}
在此,我们展示了一种计算协议,用于分析给定的一组共表达基因的启动子区域,并通过使用网络服务技术来实现该协议。该协议旨在将一组共调控基因聚类为显示相似转录因子结合位点配置的基因子集。此协议的所有步骤均已开发为符合BioMoby规范的网络服务。
{http://genome.imim.es/cgi-bin/moby/GeneClustering_DataSubmission.cgi}。