Tuite David J, Kessel David O, Nicholson Anthony A, Patel Jai V, McPherson Simon J, Shaw David R
Department of Vascular and Interventional Radiology, The Leeds Teaching Hospitals NHS Trust, St. James University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Cardiovasc Intervent Radiol. 2007 Jul-Aug;30(4):650-4. doi: 10.1007/s00270-007-9044-3.
The Amplatzer Vascular Plug (AVP) is a self-expanding nitinol wire mesh vascular embolization device derived from the Amplatz septal occluder. We assessed the results of vascular embolization obtained using the AVP.
A retrospective review was carried out of 23 consecutive cases of vascular embolization using the AVP in a variety of different clinical settings. The AVP was chosen to have a diameter approximately 30-50% greater than the target vessel. The device was delivered via an appropriately sized guide catheter and was released when satisfactorily positioned. Additional embolic agents were used in some cases.
All target vessels were successfully occluded with no device malpositioning or malfunction. In 14 (61%) patients the AVP was the sole embolic material. In the remaining patients additional agents were used, particularly in preoperative embolization of highly vascular renal tumors. The AVP does not cause instantaneous thrombosis and in high-flow situations thrombosis typically takes up to 15 min.
The AVP is a safe, effective embolization device that provides a useful adjunct to the therapeutic armamentarium. It is particularly suited to the treatment of short high-flow vessels where coil migration and catheter dislodgment might occur. In the majority of cases no additional embolic agents are necessary but it may take up to 15 min for complete thrombosis to occur.
Amplatzer血管塞（AVP）是一种由Amplatz房间隔封堵器衍生而来的自膨胀镍钛合金丝网血管栓塞装置。我们评估了使用AVP进行血管栓塞的结果。
对连续23例在各种不同临床情况下使用AVP进行血管栓塞的病例进行回顾性研究。选择的AVP直径比目标血管大约大30%至50%。该装置通过适当尺寸的引导导管输送，并在满意定位后释放。部分病例使用了额外的栓塞剂。
所有目标血管均成功闭塞，无装置位置不当或故障。14例（61%）患者中，AVP是唯一的栓塞材料。其余患者使用了额外的栓塞剂，特别是在高血供肾肿瘤的术前栓塞中。AVP不会导致即刻血栓形成，在高流量情况下血栓形成通常需要15分钟。
AVP是一种安全、有效的栓塞装置，为治疗手段提供了有用的辅助。它特别适用于治疗可能发生线圈移位和导管脱位的短高流量血管。在大多数情况下，无需额外的栓塞剂，但完全血栓形成可能需要长达15分钟。
