Carter J Elliot, Nelson John J, Eves Matthew, Boudreaux Carole
University of South Alabama, Department of Pathology, Mobile, Alabama 36617, USA.
Diagn Cytopathol. 2007 Jun;35(6):363-5. doi: 10.1002/dc.20636.
The protozoan Giardia lamblia is a major cause of gastrointestinal disease worldwide. We report the case of a 59-yr-old male who presented to his primary care physician with complaints of abdominal pain and weight loss. Imaging studies revealed a liver mass and a pancreatic head mass. Biopsy of the liver mass proved to be benign, and endoscopic ultrasound-guided fine-needle aspiration of the mass in the head of the pancreas showed no evidence of malignancy; however, numerous pear-shaped, binucleated, flagellated organisms morphologically consistent with trophozoites of Giardia lamblia were identified in the specimen. With the increasing use of endoscopic ultrasound-guided fine-needle aspiration for sampling of gastrointestinal, hepatobiliary, and pancreatic lesions, cytopathologists examining such specimens will need to be familiar with the diagnostic characteristics of this protozoal parasite.
原生动物蓝氏贾第鞭毛虫是全球胃肠道疾病的主要病因。我们报告一例59岁男性病例，该患者因腹痛和体重减轻就诊于其初级保健医生处。影像学检查发现肝脏有肿块和胰头有肿块。肝脏肿块活检证明为良性，内镜超声引导下对胰头肿块进行细针穿刺抽吸未发现恶性证据；然而，在标本中发现了许多形态上与蓝氏贾第鞭毛虫滋养体一致的梨形、双核、有鞭毛的生物体。随着内镜超声引导下细针穿刺抽吸在胃肠道、肝胆和胰腺病变采样中的应用日益增加，检查此类标本的细胞病理学家需要熟悉这种原生动物寄生虫的诊断特征。
