DeRogatis Leonard R, Burnett Arthur L
Center for Sexual Medicine at Sheppard Pratt, Baltimore, MD, USA;; Department of Psychiatry, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital and The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital and The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
J Sex Med. 2007 May;4(3):527-537. doi: 10.1111/j.1743-6109.2007.00485.x.
The field of research in sexual medicine has grown dramatically in the past decade to a point where we now have a substantial armamentarium of pharmacologic and psychological interventions available for the treatment of sexual dysfunctions in men. Concomitantly, numerous new compounds are in advanced stages of clinical development to expand the spectrum of treatment options for women's sexual dysfunctions as well. We believe we have reached a point in our overall research agenda where it may be useful to reappraise certain aspects of our clinical research methodology. We have performed this with a view toward identifying a number of key issues that we believe represent continuing impediments to sustained growth in sexual medicine research, and we have made recommendations concerning implementing tactics and strategies that we believe will help overcome these methodological barriers to continued progress. We do not view the suggestions made here as definitive resolutions to the problems identified, but rather as progressive ideas that will enable our research to continue to move forward.
在过去十年中,性医学研究领域取得了显著发展,如今我们拥有大量用于治疗男性性功能障碍的药物和心理干预手段。与此同时,众多新化合物正处于临床开发的高级阶段,以扩大女性性功能障碍的治疗选择范围。我们认为,在整体研究议程上,我们已经到了一个重新评估临床研究方法某些方面可能会有所帮助的阶段。我们这样做是为了识别一些关键问题,我们认为这些问题持续阻碍着性医学研究的持续增长,并且我们针对实施策略提出了建议,我们相信这些策略将有助于克服这些方法学障碍,推动研究持续进步。我们并不认为这里提出的建议是对所识别问题的最终解决方案,而是将其视为能使我们的研究继续前进的进步理念。