Scherl Dale S, Coffman Lori, Van Cleave Misty, Lowry Steve
Hill's Pet Nutrition, Topeka, KS 66617-1587, USA.
J Vet Dent. 2007 Mar;24(1):14-20. doi: 10.1177/089875640702400103.
Current methods for the quantification of plaque accumulation in cats and dogs are well-accepted adaptations of traditional human models, but have required substantial modifications in order to compensate for the inherent differences in compliance, cooperation, and temperament between animals and humans. While these modifications have sought to maintain or improve upon the accuracy and reproducibility of the original methods, they also have increased the complexity of the technique and have required additional scorer time and animal cooperation, which leads to increased cost of trials. Therefore, research was directed toward the development and validation of a new substrate scoring system that reduces resources while maintaining or increasing the reproducibility attributed to the more traditional methods. This new gingival contour plaque index was shown to be accurate and reproducible, but used fewer animals, required less time, and eliminated the need for many of the specialized procedures required by traditional methods.
目前用于量化猫和狗牙菌斑堆积的方法是对传统人类模型的公认改编，但为了弥补动物和人类在依从性、合作性和性情方面的固有差异，需要进行大量修改。虽然这些修改旨在保持或提高原始方法的准确性和可重复性，但它们也增加了技术的复杂性，需要额外的评分时间和动物合作，这导致试验成本增加。因此，研究方向是开发和验证一种新的底物评分系统，该系统在减少资源的同时，保持或提高归因于更传统方法的可重复性。这种新的牙龈轮廓菌斑指数被证明是准确且可重复的，但使用的动物更少，所需时间更少，并且无需传统方法所需的许多专门程序。
