Hort W
Pathologisches Institut der Universität, Düsseldorf.
Versicherungsmedizin. 1991 Oct 1;43(5):151-4.
In coronary heart disease ruptures of atherosclerotic plaques have a key position. As a rule plaque fissuring develops in the fibrous cap of a complex atherosclerotic plaque with necrotic core. In myocardial infarction in nearly all cases mural or occlusive thrombi develop as a consequence of plaque ruptures. In instable angina, too, plaques with ruptured surfaces are very numerous but often thrombi are smaller than in patients dying from myocardial infarction. Also in cases of sudden death plaque fissurings are frequently observed. Dynamic thrombi covering plaque ruptures may be sources of microemboli in the myocardium.
在冠心病中，动脉粥样硬化斑块破裂具有关键地位。通常情况下，斑块破裂发生在伴有坏死核心的复杂动脉粥样硬化斑块的纤维帽中。在心肌梗死中，几乎所有病例都会因斑块破裂而形成壁内血栓或闭塞性血栓。在不稳定型心绞痛中，表面破裂的斑块也非常多见，但血栓通常比死于心肌梗死的患者中的血栓小。在猝死病例中也经常观察到斑块破裂。覆盖斑块破裂处的动态血栓可能是心肌微栓子的来源。
