Braddock Martin
Discovery Bioscience, AstraZeneca R&D Charnwood, Loughborough, Leicestershire, England, UK.
Expert Opin Investig Drugs. 2007 Jun;16(6):909-17. doi: 10.1517/13543784.16.6.909.
The Strategic Research Institute (SRi) hosted the 11th International Inflammation and Immune Diseases Drug Discovery and Development World Summit in San Francisco during 12-13 March 2007. The summit comprised keynote sessions and two parallel tracks and focussed on targeting mechanisms for drug discovery and development, which modulate the immune response and which have anti-inflammatory activity in a number of human diseases. Indications included psoriasis, hepatitis C, allergic dermatitis, systemic lupus erythematosus, rheumatoid arthritis and osteoarthritis, multiple sclnerosis, cardiovascular disease and asthma. Data were presented supporting all stages of drug discovery from target identification and validation through to lead identification and optimisation to both early- and late-stage clinical development.
战略研究机构（SRi）于2007年3月12日至13日在旧金山举办了第11届国际炎症与免疫疾病药物发现与开发世界峰会。此次峰会包括主题演讲环节和两条并行的分议题讨论，重点关注药物发现与开发的靶向机制，这些机制可调节免疫反应，并在多种人类疾病中具有抗炎活性。涉及的病症包括银屑病、丙型肝炎、过敏性皮炎、系统性红斑狼疮、类风湿性关节炎和骨关节炎、多发性硬化症、心血管疾病和哮喘。会上展示了从靶点识别与验证到先导化合物识别与优化，再到早期和晚期临床开发等药物发现各个阶段的相关数据。
