Song Jin-Ning, Liu Shou-Xun, Bao Gang, Liang Qi, Zhang Xiao-Dong, Wang Tuo, Xie Wan-Fu, Wang Mao-de, Xie Chang-Hou
Department of Neurosurgery, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
Zhonghua Wai Ke Za Zhi. 2007 Feb 15;45(4):233-6.
To discuss the early diagnostic methods and therapeutic principles of aneurysmal subarachnoid hemorrhage (SAH), and evaluate the therapeutic efficacy objectively.
Using neuro-imaging examinations combined with case history and clinical symptoms to make the early diagnosis of 96 case with aneurysmal SAH, and Guglielmi detachable microcoil (GDC) was utilized for early intracapsular embolization in the ruptured aneurysms. Efficient symptomatic treatment was done early after operation.
All of 96 cases were early diagnosed and successfully embolized; Among them, the aneurysmal lumen was 100% occluded in 83 cases, 95% in 8 cases, 90% in 5 cases. There were 3 cases complicating with aneurysms rupture during operation, 5 cases with cerebral vasospasm. One case was affected by microcoil terminal escape after operation, 3 recurrent cases were all cured with secondary GDC embolization. There were 9 complications associated with embolization techniques and 13 cases (13.5%) occurring permanent sequelae associated with SAH. According to the Glasgow prognosis score, 77 patients got grade I, 7 grade II, 6 grade III, 3 grade IV, and 3 grade V. The mortality rate was 3.1%.
To make early etiological diagnosis of the SAH patients, using GDC to embolize the aneurysms, and earlier efficient symptomatic treatment are important methods to improve the curative rate and reduce the mortality rate.
探讨动脉瘤性蛛网膜下腔出血(SAH)的早期诊断方法及治疗原则,并客观评估治疗效果。
采用神经影像学检查结合病史及临床症状,对96例动脉瘤性SAH患者进行早期诊断,应用 Guglielmi 可脱性微弹簧圈(GDC)对破裂动脉瘤进行早期囊内栓塞,并于术后早期进行有效的对症治疗。
96例患者均早期确诊并成功栓塞;其中,动脉瘤腔完全闭塞83例(100%),95%闭塞8例,90%闭塞5例。术中动脉瘤破裂3例,脑血管痉挛5例。术后微弹簧圈末端脱出1例,复发病例3例经二次GDC栓塞均治愈。与栓塞技术相关的并发症9例,与SAH相关的永久性后遗症13例(13.5%)。根据格拉斯哥预后评分,Ⅰ级77例,Ⅱ级7例,Ⅲ级6例,Ⅳ级3例,Ⅴ级3例。死亡率为3.1%。
对SAH患者尽早进行病因诊断,应用GDC栓塞动脉瘤,并尽早进行有效的对症治疗,是提高治愈率、降低死亡率的重要方法。