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[脊柱转移瘤所致脊髓压迫症的诊断与多学科治疗]

[Diagnosis and interdisciplinary therapy of spinal cord compression caused by spinal metastases].

作者信息

Reith C, Reith H B, Baumgärtner D, Kozuschek W, Lausberg G

机构信息

Neurochirurgische Universitätsklinik, Knappschaftskrankenhauses Bochum-Langendreer, Bundesrepublik Deutschland.

出版信息

Zentralbl Chir. 1991;116(15):913-6.

PMID:1750286
Abstract

Metastatic tumours of the bone system occur up to 60% in the spinal cord. The epidural spinal cord compression is also found by metastatic tumour, so patients with metastatic disease in this localisation carry a poor prognosis. From 1986 to 1988 35 patients with symptomatic spine metastasis are operated upon. 43% of these patients recover their capability of walking. 90% from the operated collective show a reduction of pain. The primary tumour is first found from cancer of the lung and second from the kidneys. The most common localisation of metastatic tumour is the thoracic spine. The ratio from male to female is 2:1. If the risk of operation and differential therapy is discussed, the decompression and tumour resection will be the first. The concept for postoperative mobilisation and therapy concludes the stabilisation of spinal cord with internal fixation. Treatment of metastatic tumours takes aim at the improvement of life quality.

摘要

骨系统转移性肿瘤在脊髓中发生率高达60%。硬膜外脊髓压迫也可由转移性肿瘤引起,因此在此部位发生转移性疾病的患者预后较差。1986年至1988年,对35例有症状的脊柱转移患者进行了手术。这些患者中有43%恢复了行走能力。手术组中90%的患者疼痛减轻。原发肿瘤首先发现于肺癌,其次是肾癌。转移性肿瘤最常见的部位是胸椎。男女比例为2:1。在讨论手术风险和鉴别治疗时,减压和肿瘤切除将是首要选择。术后活动和治疗的理念包括通过内固定稳定脊髓。转移性肿瘤的治疗旨在提高生活质量。

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