肺炎克雷伯菌在微需氧条件下由甘油微生物生产1,3-丙二醇直至中试规模。
Microbial production of 1,3-propanediol from glycerol by Klebsiella pneumoniae under micro-aerobic conditions up to a pilot scale.
作者信息
Liu Hai-Jun, Zhang Dai-Jia, Xu You-Hai, Mu Ying, Sun Ya-Qin, Xiu Zhi-Long
机构信息
Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian, 116024, P.R. China.
出版信息
Biotechnol Lett. 2007 Aug;29(8):1281-5. doi: 10.1007/s10529-007-9398-2. Epub 2007 May 15.
1,3-Propanediol (1,3-PD) can be produced from glycerol by Klebsiella pneumoniae under micro-aerobic conditions. Recently, this fed-batch fermentation process has been successfully scaled up to 1 m(3). The final 1,3-PD concentration, molar yield and volumetric productivity of 72 g l(-1), 57% and 2.1 g l(-1 )h(-1), respectively, are close to those of 75 g l(-1), 61%, and 2.2 g l(-1 )h(-1) under anaerobic conditions. This process would be suitable for the production of 1,3-PD on a large scale.
肺炎克雷伯氏菌在微需氧条件下可利用甘油生产1,3 - 丙二醇（1,3 - PD）。最近，这种分批补料发酵工艺已成功扩大到1立方米规模。最终1,3 - PD浓度、摩尔产率和体积产率分别为72 g l⁻¹、57%和2.1 g l⁻¹ h⁻¹，接近厌氧条件下75 g l⁻¹、61%和2.2 g l⁻¹ h⁻¹的水平。该工艺适合大规模生产1,3 - PD。
Zotero 插件