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Beneficial effect of sodium sucrose-sulfate on the ocular surface of patients with severe KCS in primary Sjögren's syndrome.

作者信息

Prause J U

机构信息

Eye Pathology Institute, University of Copenhagen, Denmark.

出版信息

Acta Ophthalmol (Copenh). 1991 Aug;69(4):417-21. doi: 10.1111/j.1755-3768.1991.tb02015.x.

DOI:10.1111/j.1755-3768.1991.tb02015.x
PMID:1750307
Abstract

Sucralfate (aluminium sucrose-sulfate), a well known gastric mucosal protectant, has been tested topically on 22 patients (20 females and 2 males) suffering from primary Sjögren's syndrome. Median treatment period was 6 months (range 1-19 months). Statistically significant improvement in the ocular surface condition was found judged from the reduction in Rose-Bengal score (P less than or equal to 0.00005). The beneficial effect appeared within the first 1-4 months of treatment. No adverse side effects were encountered.

摘要

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