Borges Guilherme, Angst Jules, Nock Matthew K, Ruscio Ayelet Meron, Kessler Ronald C
National Institute of Psychiatry, Mexico.
J Affect Disord. 2008 Jan;105(1-3):25-33. doi: 10.1016/j.jad.2007.01.036. Epub 2007 May 16.
We report prospective associations of baseline risk factors with the first onset and persistence of suicide-related outcomes (SROs; ideation, plans, gestures, and attempts) over a 10-year interval among respondents who participated in both the 1990-02 National Comorbidity Survey (NCS) and the 2000-02 National Comorbidity Survey follow-up (NCS-2).
A total of 5001 NCS respondents were re-interviewed (87.6% of baseline sample) in the NCS-2. Three sets of baseline (NCS) risk factors were considered as predictors of the first onset and persistence of SROs: socio-demographics, lifetime DSM-III-R disorders, and SROs.
New onsets included 6.2% suicide ideation, 2.3% plan, 0.7% gesture, and 0.9% attempts. More than one-third of respondents with a baseline history of suicide ideation continued to have suicide ideation at some time over the intervening decade. Persistence was lower for other SROs. The strongest predictors of later SROs were baseline SROs. Prospective associations of baseline mental disorders with later SROs were largely limited to the onset and persistence of ideation.
Although data were gathered prospectively, they were based on retrospective reports at both baseline and follow-up.
Baseline history of SROs explained much of the association of mental disorders with later SROs. It is important clinically to note that many of the risk factors known to predict onset of SROs also predict persistence of SROs.
我们报告了在参与1990 - 2002年全国共病调查(NCS)和2000 - 2002年全国共病调查随访(NCS - 2)的受访者中,基线风险因素与10年间自杀相关结局(SROs;意念、计划、行为和企图)首次发生及持续存在之间的前瞻性关联。
共有5001名NCS受访者在NCS - 2中接受了重新访谈(占基线样本的87.6%)。三组基线(NCS)风险因素被视为SROs首次发生及持续存在的预测因素:社会人口统计学因素、终生DSM - III - R障碍以及SROs。
新出现的情况包括6.2%有自杀意念、2.3%有自杀计划、0.7%有自杀行为、0.9%有自杀企图。在基线时有自杀意念史的受访者中,超过三分之一在随后的十年中某个时候仍有自杀意念。其他SROs的持续存在率较低。后期SROs的最强预测因素是基线SROs。基线精神障碍与后期SROs之间前瞻性关联主要限于意念的发生和持续存在方面。
尽管数据是前瞻性收集,但它们基于基线和随访时回顾性报告。
SROs的基线病史解释了精神障碍与后期SROs之间的大部分关联。临床上需要注意的是,许多已知可预测SROs发生的风险因素也可预测SROs的持续存在情况。