Lo Y L, Tan Y E, Dan Y F, Leoh T H, Tan S B, Tan C T, Chan L L
Dept. of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
J Neurol. 2007 Jan;254(1):14-9. doi: 10.1007/s00415-007-0142-6. Epub 2007 Feb 14.
The clinical diagnosis of cervical spondylotic myelopathy (CSM) may be challenging in patients with cervical spondylosis (CS). Routine nerve conduction studies (NCS) may not evaluate cord compression adequately.
We obtained cutaneous silent periods (CSP) in 26 consecutive patients presenting with clinical features of CS, in comparison with 30 normal controls. The results were also compared with transcranial magnetic stimulation (TMS) findings, and magnetic resonance imaging of the cervical cord as the gold standard.
CSP findings showed similarly high sensitivity of up to 96% with TMS in evaluating cervical cord dysfunction.
In specific clinical settings, CSP is of value for the diagnosis of CSM in CS. CSP measurement is advocated as a simple and rapid diagnostic adjunct to NCS in evaluating CS patients with possible cord compromise.
颈椎病性脊髓病（CSM）在颈椎病（CS）患者中的临床诊断可能具有挑战性。常规神经传导研究（NCS）可能无法充分评估脊髓压迫情况。
我们对26例具有CS临床特征的连续患者进行了皮肤静息期（CSP）测定，并与30名正常对照者进行比较。结果还与经颅磁刺激（TMS）结果以及作为金标准的颈髓磁共振成像进行了比较。
在评估颈髓功能障碍方面，CSP结果显示出与TMS相似的高达96%的高敏感性。
在特定临床情况下，CSP对CS中CSM的诊断具有价值。在评估可能存在脊髓损伤的CS患者时，提倡将CSP测量作为NCS的一种简单快速的诊断辅助手段。
