Abouassaly Robert, Angermeier Kenneth W
Section of Presthetic Surgery and Genitourethral Reconstruction, Glickman Urological Institute A/100, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
J Urol. 2007 Jun;177(6):2211-5; discussion 2215-6. doi: 10.1016/j.juro.2007.01.140.
During substitution urethroplasty, if the stricture contains a 1 to 2 cm region that is particularly narrow and/or fibrotic, that portion may be excised with subsequent anastomosis of the dorsal or ventral aspect of the urethra to shorten, widen and optimize the urethral wall onto which an onlay graft is to be placed. This procedure is termed augmented anastomotic urethroplasty. To determine the effectiveness of this approach we reviewed our experience with augmented anastomotic urethroplasty in an 8-year period.
We reviewed the records of patients who underwent augmented anastomotic urethroplasty between October 1997 and April 2005. Perioperative characteristics were compared between successes and failures using the Wilcoxon/Kruskal-Wallis and Fisher exact tests.
Of 69 patients who underwent augmented anastomotic urethroplasty for recurrent urethral strictures 5 had undergone previous urethroplasty using a genital skin flap or graft. At a median followup of 34 months (range 13 to 103) 62 patients had no evidence of stricture recurrence and required no further intervention for an overall success rate of 90%. Stricture recurrence, defined as the inability to easily pass a standard flexible cystoscope through the area of repair, occurred in 7 patients (10%). Patients with stricture recurrence were significantly older (mean age 52 vs 39 years, p = 0.02) and more likely to experience postoperative urinary tract infection (28% vs 3.2%, p = 0.05) than patients without repeat stricture.
Augmented anastomotic urethroplasty is an effective technique that allows the use of a shorter onlay graft. It may optimize overall results due to improvement in the urethral wall and the associated corpus spongiosum.
在替代尿道成形术中,如果狭窄包含一段1至2厘米特别狭窄和/或纤维化的区域,可将该部分切除,随后进行尿道背侧或腹侧吻合,以缩短、加宽并优化将要放置覆盖移植物的尿道壁。此手术称为增强吻合性尿道成形术。为确定该方法的有效性,我们回顾了8年间增强吻合性尿道成形术的经验。
我们回顾了1997年10月至2005年4月间接受增强吻合性尿道成形术患者的记录。使用Wilcoxon/Kruskal-Wallis检验和Fisher精确检验比较成功与失败患者的围手术期特征。
69例因复发性尿道狭窄接受增强吻合性尿道成形术的患者中,5例曾使用生殖器皮瓣或移植物进行过尿道成形术。中位随访34个月(范围13至103个月),62例患者无狭窄复发迹象,无需进一步干预,总体成功率为90%。7例患者(10%)出现狭窄复发,定义为无法轻松通过标准软性膀胱镜通过修复区域。与无再次狭窄的患者相比,狭窄复发患者年龄显著更大(平均年龄52岁对39岁,p = 0.02),术后发生尿路感染的可能性更高(28%对3.2%,p = 0.05)。
增强吻合性尿道成形术是一种有效的技术,可使用较短的覆盖移植物。由于尿道壁及相关海绵体的改善,它可能优化总体效果。