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白膜与颊黏膜移植尿道成形术治疗前尿道狭窄:一项前瞻性随机对照试验研究

Tunica albuginea versus buccal mucosa graft urethroplasty for anterior urethral stricture: A prospective randomised pilot study.

作者信息

Faridi Mohammad Shazib, Sharma Vikas, Sharma Adittya K, Yadav Rahul

机构信息

Division of Urology, Department of Surgery, Hamdard Institute of Medical Sciences & Research and HAHC Hospital, New Delhi, India.

Department of Urology, Rajiv Gandhi Super Speciality Hospital, Tahirpur, Delhi, India.

出版信息

Asian J Urol. 2023 Apr;10(2):189-194. doi: 10.1016/j.ajur.2021.12.003. Epub 2021 Dec 28.

Abstract

OBJECTIVE

The objective of the study was to compare the outcome of tunica albuginea urethroplasty (TAU) and buccal mucosa graft (BMG) urethroplasty for anterior urethral stricture.

METHODS

Thirty patients who met the inclusion criteria were randomised into two groups: TAU (Group A) and BMG urethroplasty (Group B). Surgical outcome was evaluated with pre- and post-operative work-up involving retrograde urethrogram, voiding cystourethrogram, uroflowmetry, and urethroscopy. Patients were followed up till 1 year.

RESULTS

Mean duration of surgery was statistically significant between two groups (=0.0005). Maximum urine flow rate was comparable when compared between two groups (=0.22) but statistically significant when compared pre- and post-operatively (<0.001). At follow-up of 1 year, the successful outcomes were 80% in Group A and 87% in Group B. A total of five patients who had unsuccessful results required redo urethroplasty. Complications were minimal in both the groups.

CONCLUSION

TAU provides outcomes equivalent to those of BMG urethroplasty. TAU has less operative time, easy to perform, and beneficial in patients with poor oral hygiene.

摘要

目的

本研究的目的是比较白膜尿道成形术(TAU)和颊黏膜移植(BMG)尿道成形术治疗前尿道狭窄的疗效。

方法

30例符合纳入标准的患者被随机分为两组:TAU组(A组)和BMG尿道成形术组(B组)。通过术前和术后的检查,包括逆行尿道造影、排尿性膀胱尿道造影、尿流率测定和尿道镜检查来评估手术效果。对患者进行随访直至1年。

结果

两组之间的平均手术时间有统计学意义(=0.0005)。两组之间的最大尿流率具有可比性(=0.22),但术前和术后比较有统计学意义(<0.001)。在1年的随访中,A组的成功结果为80%,B组为87%。共有5例手术结果不成功的患者需要再次进行尿道成形术。两组的并发症都很少。

结论

TAU的疗效与BMG尿道成形术相当。TAU手术时间较短,操作简便,对口腔卫生较差的患者有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc77/10023540/9b210f06a26a/gr1.jpg

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