Haverkamp W, Hindricks G, Borggrefe M, Budde T, Breithardt G
Grud Serdechnososudistaia Khir. 1991 Aug(8):6-16.
Trans-catheteral ablation is an important therapeutic method for nonpharmacological management of various types of cardiac arrhythmias. Since its introduction into clinical practice in 1982, it has proved its efficacy in disturbance or change of the type of atrioventricular conduction and conduction along accessory abnormal atrioventricular conduction pathways. Positive results have also been attained in the treatment of some patients with ventricular tachycardia. The energy sources used for ablation include direct current pulses possessing large energy, high-frequency currents, and laser energy. Ablation with direct current and high-frequency current is already used successfully in patients, while the use of laser energy for ablation of myocardial arrhythmogenic tissue is limited mainly to operations on the open heart. The use of alternating high-frequency current has attracted particular attention in the last years. Trans-coronary chemical ablation is another recently introduced method which is not connected with the use of electric current. Only experimental and a small clinical experience with this new method has been gained to date. This survey systemasizes the current knowledge of the biophysical bases of the various method of ablation from the standpoint of the mechanisms of treatment, the methodology and the main types of tissue response. Clinical experience with trans-catheteral treatment of cardiac arrhythmias is analysed.
经导管消融是各种类型心律失常非药物治疗的重要方法。自1982年引入临床实践以来,它已在房室传导类型的干扰或改变以及沿异常房室旁道的传导方面证明了其有效性。在一些室性心动过速患者的治疗中也取得了积极成果。用于消融的能量来源包括具有大能量的直流脉冲、高频电流和激光能量。直流电和高频电流消融已成功应用于患者,而激光能量用于消融心肌致心律失常组织主要限于心脏直视手术。近年来,交变高频电流的应用引起了特别关注。经冠状动脉化学消融是最近引入的另一种与电流使用无关的方法。迄今为止,仅获得了关于这种新方法的实验和少量临床经验。本综述从治疗机制、方法和主要组织反应类型的角度,系统总结了各种消融方法的生物物理基础的当前知识。分析了经导管治疗心律失常的临床经验。