Caylak Emrah
Department of Biochemistry and Clinical Biochemistry, Firat University, School of Medicine, Elazig, Turkey.
Am J Med Genet B Neuropsychiatr Genet. 2007 Oct 5;144B(7):923-43. doi: 10.1002/ajmg.b.30537.
Learning disorders (LD) commonly comprise of a heterogeneous group of disorders manifested by unexpected problems in some children's experiences in the academic performance arena. These problems especially comprise of a variety of disorders which may be subclassified to attention-deficit hyperactivity disorder (ADHD), reading disability (RD), specific language impairment (SLI), speech-sound disorder (SSD), and dyspraxia. The aim of this review is to summarize the current molecular studies and some of the most exciting recent developments in molecular genetic research on LD. The findings for the association and linkage of LD with candidate genes will help to set the research agendas for future studies to follow.
学习障碍(LD)通常由一组异质性障碍组成,表现为一些儿童在学业成绩方面出现意外问题。这些问题尤其包括多种障碍,可细分为注意力缺陷多动障碍(ADHD)、阅读障碍(RD)、特定语言障碍(SLI)、语音障碍(SSD)和发育性运动障碍。本综述的目的是总结当前关于学习障碍的分子研究以及分子遗传学研究中一些最令人兴奋的最新进展。学习障碍与候选基因的关联和连锁研究结果将有助于确定未来研究的议程。