Shriberg Lawrence D, Lohmeier Heather L, Strand Edythe A, Jakielski Kathy J
Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA.
Clin Linguist Phon. 2012 May;26(5):445-82. doi: 10.3109/02699206.2012.655841.
A central question in Childhood Apraxia of Speech (CAS) is whether the core phenotype is limited to transcoding (planning/programming) deficits or if speakers with CAS also have deficits in auditory-perceptual encoding (representational) and/or memory (storage and retrieval of representations) processes. We addressed this and other questions using responses to the Syllable Repetition Task (SRT) [Shriberg, L. D., Lohmeier, H. L., Campbell, T. F., Dollaghan, C. A., Green, J. R., & Moore, C. A. (2009). A nonword repetition task for speakers with misarticulations: The syllable repetition task (SRT). Journal of Speech, Language, and Hearing Research, 52, 1189-1212]. The SRT was administered to 369 individuals in four groups: (a) typical speech-language (119), (b) speech delay-typical language (140), (c) speech delay-language impairment (70), and (d) idiopathic or neurogenetic CAS (40). CAS participants had significantly lower SRT competence, encoding, memory, and transcoding scores than controls. They were 8.3 times more likely than controls to have SRT transcoding scores below 80%. We conclude that speakers with CAS have speech processing deficits in encoding, memory, and transcoding. The SRT currently has moderate diagnostic accuracy to identify transcoding deficits, the signature feature of CAS.
言语失用症（CAS）的一个核心问题是，其核心表型是否仅限于转码（计划/编程）缺陷，或者患有CAS的说话者在听觉感知编码（表征）和/或记忆（表征的存储和检索）过程中是否也存在缺陷。我们通过对音节重复任务（SRT）的反应来解决这个问题以及其他问题[施里伯格，L.D.，洛迈尔，H.L.，坎贝尔，T.F.，多拉根，C.A.，格林，J.R.，&摩尔，C.A.（2009年）。针对发音错误者的非词重复任务：音节重复任务（SRT）。《言语、语言和听觉研究杂志》，52，1189 - 1212]。对四组共369名个体进行了SRT测试：（a）典型言语 - 语言组（119人），（b）言语延迟 - 典型语言组（140人），（c）言语延迟 - 语言障碍组（70人），以及（d）特发性或神经遗传性CAS组（40人）。与对照组相比，患有CAS的参与者在SRT能力、编码、记忆和转码得分上显著更低。他们的SRT转码得分低于80%的可能性是对照组的8.3倍。我们得出结论，患有CAS的说话者在编码、记忆和转码方面存在言语处理缺陷。目前，SRT在识别转码缺陷（CAS的标志性特征）方面具有中等诊断准确性。
