Harris Katharine B, Pass Kenneth A
New York State Department of Health, Wadsworth Center, Laboratory of Molecular Screening Technologies, Empire State Plaza, Albany, NY 12201, USA.
Mol Genet Metab. 2007 Jul;91(3):268-77. doi: 10.1016/j.ymgme.2007.03.012. Epub 2007 May 23.
Mandated screening of newborns for congenital hypothyroidism (CH) in NYS was initiated in l978. Currently, every newborn screening program in the U.S. includes CH in its panel. Between 1978 and 2005, 7.4 million newborns were screened for CH in NYS. In NYS, between 1978 and 2005, the incidence of CH has increased by 138%. Nationwide (excluding NYS data), with nearly 58 million infants screened between 1987 and 2002, the incidence has increased 73% between 1987 and 2002. These data and possible reasons for the increases are discussed, though no definitive causes are identified.
纽约州于1978年开始强制对新生儿进行先天性甲状腺功能减退症（CH）筛查。目前，美国的每个新生儿筛查项目都将CH纳入筛查范围。1978年至2005年期间，纽约州有740万新生儿接受了CH筛查。在纽约州，1978年至2005年期间，CH的发病率增长了138%。在全国范围内（不包括纽约州的数据），1987年至2002年期间有近5800万婴儿接受了筛查，1987年至2002年期间发病率增长了73%。本文讨论了这些数据以及发病率上升的可能原因，不过尚未确定确切病因。
