Allford M A
Department of Anaesthesia, York Hospital, Wigginton Road, York YO31 8ZZ, UK.
Br J Anaesth. 2007 Aug;99(2):218-20. doi: 10.1093/bja/aem130. Epub 2007 May 18.
This is the report of a 55-yr-old female who developed severe myotonia and dystonia after general anaesthesia. Before starting on gabapentin therapy for a neuropathic pain condition, she had undergone numerous uneventful general anaesthetics. Since receiving treatment with gabapentin, she has experienced severe movement disorders on emergence from each subsequent general anaesthetic. The events were unrelated to the choice of anaesthetic or anti-emetic. The most recent event that required a protracted stay in hospital after a day-case surgery is presented in detail, and the possible mechanisms to explain the interaction are discussed.
这是一名55岁女性的病例报告，该患者在全身麻醉后出现了严重的肌强直和肌张力障碍。在开始使用加巴喷丁治疗神经性疼痛之前，她曾多次顺利接受全身麻醉。自从接受加巴喷丁治疗后，她在每次后续全身麻醉苏醒时都出现了严重的运动障碍。这些事件与麻醉剂或止吐药的选择无关。详细介绍了最近一次在日间手术术后需要长期住院的事件，并讨论了解释这种相互作用的可能机制。
