Jain Sumita, Goldberg Marcia B
Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital/Harvard Medical School, Cambridge, MA 02139, USA.
J Bacteriol. 2007 Jul;189(14):5393-8. doi: 10.1128/JB.00228-07. Epub 2007 May 18.
Autotransporters constitute the largest group of secreted proteins in gram-negative bacteria. Autotransporter secretion involves the insertion of a carboxy-terminal beta barrel into and the translocation of an amino-terminal domain across the outer membrane. Here, we demonstrate that secretion of autotransporters from several organisms requires the outer membrane assembly factor YaeT.
自转运蛋白是革兰氏阴性菌中分泌蛋白最大的一类。自转运蛋白分泌涉及羧基末端β桶插入外膜以及氨基末端结构域跨外膜转运。在此，我们证明来自几种生物体的自转运蛋白的分泌需要外膜组装因子YaeT。
