Kaganman Irene
Nat Methods. 2007 May;4(5):382-3. doi: 10.1038/nmeth0507-382b.
Using a directed evolution approach, researchers demonstrate a way of creating 'designer' receptors that are specifically activated by a ligand with no other biological activity in the cell.
通过定向进化方法,研究人员展示了一种创建“设计型”受体的方法,这些受体可被细胞内无其他生物活性的配体特异性激活。