Iusupova G, Jenner L, Iusupov M
Mol Biol (Mosk). 2007 Mar-Apr;41(2):274-83.
Recent X-ray and cryo-EM studies of 70S ribosome complexes containing different types of messenger RNAs (mRNA) and transfer RNA (tRNA) have been reviewed. Changes of the mRNA path on the ribosome at initiation and elongation states have been described. Authors suggested, that the specific region of ribosomal 30S subunit ("platform") is a ribosome binding site of regulatory domains of mRNA which locates on the non-translated 5'-end of the mRNA.
近期对包含不同类型信使核糖核酸(mRNA)和转运核糖核酸(tRNA)的70S核糖体复合物进行的X射线和冷冻电镜研究已得到综述。文中描述了核糖体上mRNA路径在起始和延伸状态下的变化。作者提出,核糖体30S亚基的特定区域(“平台”)是位于mRNA非翻译5'端的mRNA调控域的核糖体结合位点。