一名患有朗格汉斯细胞组织细胞增多症的成人的结痂性挪威疥疮：导致全身化疗的意外情况。
Crusted Norwegian scabies in an adult with Langerhans cell histiocytosis: mishaps leading to systemic chemotherapy.
作者信息
Kartono Francisca, Lee Edward W, Lanum David, Pham Lien, Maibach Howard I
机构信息
Western University of Health Sciences, Pomona, California, USA.
出版信息
Arch Dermatol. 2007 May;143(5):626-8. doi: 10.1001/archderm.143.5.626.
BACKGROUND
Crusted Norwegian scabies is a rare hyperkeratotic variant of scabies infestation. We report herein a case of crusted scabies in a woman with underlying Langerhans cell histiocytosis (LCH).
OBSERVATIONS
A 49-year-old woman with LCH was hospitalized owing to marked thrombocytopenia. Her hyperkeratotic skin eruption was thought to be secondary to LCH because several years earlier, she had positive biopsy findings and had been diagnosed as having LCH. After a 1-month hospital stay, her laboratory values improved despite worsening of her skin lesions.
CONCLUSION
Analysis of skin scrapings confirmed the presence of scabies, and resolution was achieved with a 1-dose ivermectin treatment.
背景
结痂性挪威疥疮是疥疮感染的一种罕见的角化过度型。我们在此报告一例患有潜在朗格汉斯细胞组织细胞增多症（LCH）的女性的结痂性疥疮病例。
观察结果
一名患有LCH的49岁女性因明显的血小板减少症住院。她的角化过度性皮疹被认为是LCH的继发表现，因为几年前她的活检结果呈阳性，被诊断为患有LCH。住院1个月后，尽管她的皮肤病变有所恶化，但实验室检查值有所改善。
结论
皮肤刮片分析证实存在疥疮，单剂量伊维菌素治疗取得了治愈效果。
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