Sakihara Kotoe, Hirata Masayuki, Nakagawa Seiji, Fujiwara Nobuko, Sekino Masaki, Ueno Shoogo, Ihara Aya, Yorifuji Shiro
Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, Yamadaoka, Suita, Osaka, Japan.
Neuroreport. 2007 Jun 11;18(9):891-4. doi: 10.1097/WNR.0b013e3280ef697a.
We previously demonstrated that late electromyographic responses with a latency of 100 ms were evoked bilaterally in soleus muscles following transcranial magnetic stimulation over the left cerebellum. Efferent fibers from the left cerebellum modulate vestibulospinal tract influences on the extensor muscles of the left hindlimb. Here, we investigated whether the vestibulospinal tract mediates this late response. We activated the vestibulospinal tract by optokinetic stimulation. Our results show that the latency of the soleus electromyographic response is shortened by optokinetic stimulation, but the latency of the motor response evoked by the corticospinal tract is unchanged. These findings support our hypothesis that vestibulospinal tracts mediate late electromyographic responses, and allow the development of techniques to assess the human vestibulospinal system function.
我们之前证明，经颅磁刺激左小脑后，双侧比目鱼肌会诱发潜伏期为100毫秒的晚期肌电图反应。来自左小脑的传出纤维调节前庭脊髓束对左后肢伸肌的影响。在此，我们研究了前庭脊髓束是否介导这种晚期反应。我们通过视动刺激激活前庭脊髓束。我们的结果表明，视动刺激可缩短比目鱼肌肌电图反应的潜伏期，但皮质脊髓束诱发的运动反应潜伏期不变。这些发现支持了我们的假设，即前庭脊髓束介导晚期肌电图反应，并有助于开发评估人类前庭脊髓系统功能的技术。
