Matsuo T, Yamada T, Matsuo M, Sakai R
Hyogo Prefectural Awaji Hospital, Sumoto, Japan.
Biomater Artif Cells Immobilization Biotechnol. 1991;19(1):185-91. doi: 10.3109/10731199109117825.
We describe a 43-year-old male patient with congenital antithrombin III deficiency requiring hemodialysis due to extension of venous thrombus from recurrent deep vein thrombosis. During dialysis with adequate heparinization, the patient often revealed clot formation in the extracorporeal circuit resulting in unexpected discontinuation of dialysis. When either a combination of antithrombin III concentrate + heparin or the newly developed synthetic antithrombin preparation, MD805, was administered during dialysis, he could be uneventfully dialyzed with either of the two regimens.
我们描述了一名43岁的男性患者，其患有先天性抗凝血酶III缺乏症，因复发性深静脉血栓形成导致静脉血栓扩展而需要进行血液透析。在充分肝素化的透析过程中，该患者体外循环中常出现凝血，导致透析意外中断。当在透析期间给予抗凝血酶III浓缩物+肝素联合治疗或新开发的合成抗凝血酶制剂MD805时，他可以通过这两种方案中的任何一种顺利进行透析。
