Atanes A, Gómez N, de Toro F J, Freire M, Soler R, Graña J, Verea H
Unidad de Reumatología, Hospital Juan Canalejo, La Coruña.
An Med Interna. 1991 Oct;8(10):481-6.
94 patients diagnosed as having sarcoidosis were studied in Galicia in order to evaluate the frequency of bone manifestations, as well as to analyse the clinical and radiological features. Bone lesions were found in 10 patients (10.6%) with a median age of 47.4 years, the predominant sex being female in this group (70%). The lesions were of two types: a) osteolytic on metacarpal (4 cases), nasal bones (1 case), sacrum (1 case), femur (1 case); b) osteosclerosis on femur and fibula (1 case), acrosclerosis (3 cases), metacarpal (1 case). The first lesions were associated to chronic types of sarcoidosis with skin and lung involvements. The second lesions were associated to a sub-acute type of Löfgren. We highlight the behaviour of both types of bone lesions and comment on the physiopathology of the sclerotic lesions.
在加利西亚对94例被诊断为结节病的患者进行了研究，以评估骨骼表现的发生率，并分析其临床和放射学特征。在10例患者（10.6%）中发现了骨病变，这些患者的中位年龄为47.4岁，该组中女性占主导地位（70%）。病变有两种类型：a）掌骨溶骨性病变（4例）、鼻骨（1例）、骶骨（1例）、股骨（1例）；b）股骨和腓骨骨硬化（1例）、肢端硬化（3例）、掌骨（1例）。第一种病变与伴有皮肤和肺部受累的慢性结节病类型相关。第二种病变与亚急性 Löfgren 型相关。我们着重介绍了两种类型骨病变的表现，并对硬化性病变的病理生理学进行了评论。
