Maruyama Jun-ichi, Kitamoto Katsuhiko
Department of Biotechnology, The University of Tokyo, Tokyo, Japan.
FEMS Microbiol Lett. 2007 Jul;272(1):1-7. doi: 10.1111/j.1574-6968.2007.00758.x. Epub 2007 May 21.
Filamentous fungi are composed of hyphal compartments divided by septa, which communicate via septal pores. Apical compartments can elongate to over 100 microm without septum formation and possess a polarized distribution of organelles. In Aspergillus, subapical compartments are arrested in interphase but can reinitiate mitosis and growth by branching. Recent reports using green fluorescent protein (GFP) technology have demonstrated the highly differentiated localization of the endoplasmic reticulum (ER) network in various regions of the hyphae: the gradient distribution from the apical region, the localization along the septum, differential distributions in adjacent compartments, and the dynamic morphological change during septum formation. In this review the spatial regulation of the ER network in multicellular filamentous fungi is discussed.
丝状真菌由被隔膜分隔的菌丝间隔组成，这些隔膜通过隔膜孔进行沟通。顶端间隔可以在不形成隔膜的情况下伸长至超过100微米，并具有细胞器的极性分布。在曲霉菌中，亚顶端间隔在间期停滞，但可以通过分支重新启动有丝分裂和生长。最近使用绿色荧光蛋白（GFP）技术的报告表明，内质网（ER）网络在菌丝的各个区域具有高度分化的定位：从顶端区域的梯度分布、沿隔膜的定位、相邻间隔中的差异分布，以及隔膜形成过程中的动态形态变化。在这篇综述中，讨论了多细胞丝状真菌中内质网网络的空间调控。
