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[HIV 阳性患者中结核病的发病率及临床表现]

[The incidence and clinical presentation of tuberculosis in HIV-positive patients].

作者信息

Jolín Garijo L, González Vilas M, Parada Castellano R, Ojea de Castro R

机构信息

Unidad de Medicina Familiar, Hospital Montecelo, Pontevedra.

出版信息

Aten Primaria. 1991 Apr;8(4):310, 312-3.

PMID:1751711
Abstract

To evaluate the features of tuberculous infection in HIV+ patients from our area we reviewed the 50 cases of seropositive patients admitted to a provincial hospital from 1985 to June 1989. TB was diagnosed in 18 of the 50 patients; mean patient age was 27 years, with a male predominance. PDA was the major risk practice. The most common localization were lymph nodes; 95% had fever and weight loss and 39% had nightly perspiration and cough; cervical lymphadenopathy and hepatosplenomegaly were found in more than 50%. Tuberculin skin test was negative in 75% of cases. The diagnosis of TB represented the diagnosis of AIDS for 66% of patients. 25 of the 50 seropositive patients met the criteria for AIDS, and 68% of these had TB. TB is a common infection in HIV+ patients from our area, and it is the first cause of the diagnosis of AIDS. The index of suspicion of TB in these patients should be high, as clinical features are often nonspecific. However, it is preventable and curable superinfection.

摘要

为评估我们地区HIV阳性患者的结核感染特征,我们回顾了1985年至1989年6月间收治于一家省级医院的50例血清学阳性患者。50例患者中有18例诊断为结核病;患者平均年龄为27岁,男性居多。共用注射器吸毒是主要的高危行为。最常见的病变部位是淋巴结;95%的患者有发热和体重减轻,39%的患者有夜间盗汗和咳嗽;超过50%的患者有颈部淋巴结肿大和肝脾肿大。75%的病例结核菌素皮肤试验呈阴性。对66%的患者而言,结核病诊断意味着艾滋病诊断。50例血清学阳性患者中有25例符合艾滋病标准,其中68%患有结核病。结核病是我们地区HIV阳性患者的常见感染,并且是艾滋病诊断的首要病因。鉴于这些患者的临床特征往往不具特异性,对结核病的怀疑指数应较高。然而,这是一种可预防和可治愈的重叠感染。

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