Lattarulo Serafina, Ugenti Ippazio, Filograna Maria Alessandra, Pezzolla Angela, Ferrarese Filippo, Fabiano Gennaro
Dipartimento di Scienze Chirurgiche Generali e Specialistiche, Cattedra di Chirurgia Generale dell'Università di Bari.
Ann Ital Chir. 2007 Jan-Feb;78(1):21-5.
The authors report on twelve cases of non-ampullary duodenal neoplasm and remark the rarity of this pathology. According to the literature, the traditional endoscopy is the mainstay diagnostic test, because of aspecific digestive symptoms, but the authors stress the importance of the "longue" endoscopy or endoscopy integrated with duodenography in non-responders patients who had non-diagnostic traditional endoscopy for neoplasm. Duodeno-cephalo-pancreatectomy and segmentary duodenal resection are proposed by tumor site. Better results for prognosis can be obtained only with an early diagnosis and radical surgical therapy, because of chemotherapy and radiotherapy don't improve survival.
作者报告了12例非壶腹十二指肠肿瘤病例，并指出这种病理情况较为罕见。根据文献，传统内镜检查是主要的诊断方法，因为有非特异性消化系统症状，但作者强调在传统内镜检查对肿瘤诊断无结果的无反应患者中，“长程”内镜检查或内镜检查结合十二指肠造影的重要性。根据肿瘤部位建议行十二指肠-胰头-胰腺切除术和十二指肠节段切除术。由于化疗和放疗不能提高生存率，只有早期诊断和根治性手术治疗才能获得更好的预后结果。
