Sanchez Julio E, Barham Kelly L, Sangueza Omar P
Department of Pathology, Wake Forest University Baptist Medical Center, Winston-Salem, NC 27157, USA.
J Cutan Pathol. 2007 Jun;34(6):490-3. doi: 10.1111/j.1600-0560.2006.00640.x.
Acrodermatitis enteropathica (ADE) is a rare genetic or acquired disorder of hypozincemia. It can be caused by impaired intestinal absorption of zinc or by poor consumption of the mineral. It is characterized by skin lesions on acral and periorificial areas and may be associated to alopecia, diarrhea and increased frequency of infections. We present an atypical presentation of ADE in a 33-year-old women with a history of mental retardation and psoriasis that presented with lesions on the periorificial areas and extremities, and low plasma zinc levels.
肠病性肢端皮炎（ADE）是一种罕见的低锌血症的遗传性或后天性疾病。它可由肠道对锌的吸收受损或矿物质摄入不足引起。其特征为肢端和口周区域出现皮肤病变，可能伴有脱发、腹泻和感染频率增加。我们报告了一名33岁女性的非典型ADE病例，该女性有智力发育迟缓及银屑病病史，表现为口周区域和四肢出现病变，且血浆锌水平较低。
