Braun-Falco O, von Liebe V
MMW Munch Med Wochenschr. 1977 Jan 14;119(2):37-42.
Treatment of acrodermatitis enteropathica with zinc sulfate, first described by Moynahan and Barnes in 1973, has been widely accepted. We have treated a case of acrodermatitis enteropathica successfully with this drug. The 14-year old boy had to discontinue clioquinol because of a partial opticus atrophy. The skin lesions deteriorated acutely. Following zinc sulfate treatment the lesions rapidly disappeared and the general health of the patient greatly improved. Small doses of zinc sulfate are sufficient for maintenance therapy. The pathogenesis of acrodermatitis enteropathica is reviewed and the modes of action of zinc therapy are considered.
1973年莫伊纳汉和巴恩斯首次描述了用硫酸锌治疗肠病性肢端皮炎，该方法已被广泛接受。我们用这种药物成功治疗了一例肠病性肢端皮炎患者。这名14岁男孩因部分视神经萎缩不得不停用氯碘喹啉。皮肤损害急剧恶化。硫酸锌治疗后，损害迅速消失，患者的整体健康状况大为改善。小剂量硫酸锌足以用于维持治疗。本文回顾了肠病性肢端皮炎的发病机制，并探讨了锌治疗的作用方式。
