Robb Christopher W, Hayes Benjamin B, Boyd Alan S
Division of Dermatology, Department of Internal Medicine, Vanderbilt University, Nashville, TN 37232, USA.
J Cutan Pathol. 2007 Jun;34(6):513-4. doi: 10.1111/j.1600-0560.2006.00657.x.
Brown recluse spider bites (BRSB) cause a myriad of reactions ranging from local necrosis to potentially lethal systemic involvement. Envenomation may induce a generalized exanthem known clinically but not described histologically. We report a 49-year-old female who developed a generalized exanthem 24 hours after BRSB. The histopathology demonstrated a necrotizing vasculitis similar to that seen at an envenomation site but without epidermal necrosis. Loxoscelism should be considered in patients residing in endemic areas who present with a vasculitic exanthem.
棕色隐士蜘蛛咬伤（BRSB）会引发一系列反应，从局部坏死到可能致命的全身累及。毒液注入可能诱发一种临床上已知但组织学上未描述的全身性皮疹。我们报告一名49岁女性，在被棕色隐士蜘蛛咬伤24小时后出现全身性皮疹。组织病理学显示为坏死性血管炎，类似于在毒液注入部位所见，但无表皮坏死。对于居住在流行地区且出现血管炎性皮疹的患者，应考虑棕色隐士蜘蛛咬伤。
