外周造血干细胞产品被与产黏液分枝杆菌相关的病原体污染。

Contamination of peripheral hematopoeitic stem cell products with a Mycobacterium mucogenicum-related pathogen.

作者信息

Kassis Imad, Oren Ilana, Davidson Sima, Finkelstein Renato, Rabino Galit, Katz Tami, Sprecher Hannah

机构信息

Infectious Diseases Unit, Meyer Children's Hospital, Rambam Medical Center, and Bruce-Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

出版信息

Infect Control Hosp Epidemiol. 2007 Jun;28(6):755-7. doi: 10.1086/516666. Epub 2007 May 15.

DOI:10.1086/516666

PMID:17520558

Abstract

A gram-positive rod with a restriction pattern closely related to the published nucleotide sequence of Mycobacterium mucogenicum was isolated from 6 of 45 units of peripheral blood stem cell products. The source of the contamination was traced to ice cubes used in processing the peripheral blood stem cell products. Substituting reusable ice trays for ice from an ice machine terminated the outbreak.

摘要

从45份外周血干细胞产品中的6份中分离出一种革兰氏阳性杆菌，其限制性酶切图谱与已发表的产黏液分枝杆菌核苷酸序列密切相关。污染源头追溯到处理外周血干细胞产品时使用的冰块。用可重复使用的冰盘代替制冰机生产的冰后，疫情得到控制。