Nagelhus Hernes Toril A, Lindseth Frank, Selbekk Tormod, Wollf Arild, Solberg Ole Vegard, Harg Erik, Rygh Ola M, Tangen Geir Arne, Rasmussen Inge, Augdal Sigmund, Couweleers Fred, Unsgaard Geirmund
SINTEF, Trondheim, Norway.
Int J Med Robot. 2006 Mar;2(1):45-59. doi: 10.1002/rcs.68.
Navigation systems are now frequently being used for guiding surgical procedures. Existing neuronavigation systems suffer from the lack of updated images when tissue changes during surgery as well as from user-friendly displays of all essential images for accurate and safe surgery guidance.
We have developed various new technologies for improved neuronavigation. Using intraoperative 3D ultrasound (US) imaging, we have developed various registration algorithms for using and updating a complete multimodal and multivolume 3D map for navigation.
We experienced that advanced multimodal visualization makes it easy to interpret information from several image volumes and modalities simultaneously. Using high quality intraoperative 3D ultrasound, essential preoperative information could be corrected due to brain shift. fMRI and other important preoperative data could then be used together with intraoperative ultrasound imaging for more accurate, safer and improved guidance of therapy.
We claim that new features, as demonstrated in the present paper, using intraoperative 3D ultrasound in combination with advanced registration and display algorithms will represent important contributions towards more accurate, safer and more optimized future patient treatment.
导航系统如今频繁用于指导外科手术。现有的神经导航系统存在手术过程中组织发生变化时缺乏更新图像的问题，以及缺乏便于用户操作的所有关键图像显示以实现准确且安全的手术指导。
我们开发了多种用于改进神经导航的新技术。利用术中三维超声（US）成像，我们开发了多种配准算法，以使用和更新用于导航的完整多模态、多体积三维地图。
我们发现先进的多模态可视化使得同时解读来自多个图像体积和模态的信息变得容易。使用高质量的术中三维超声，由于脑移位，重要的术前信息得以校正。然后，功能磁共振成像（fMRI）和其他重要的术前数据可与术中超声成像一起用于更准确、更安全且改进的治疗指导。
我们声称，如本文所展示的，将术中三维超声与先进的配准和显示算法相结合的新特性，将为未来更准确、更安全且更优化的患者治疗做出重要贡献。
